10 Best b12 supplement (2025)

10 Best B12 Supplement

When it comes to maintaining optimal health, vitamin B12 plays a crucial role. This essential nutrient is vital for nerve function, red blood cell production, and DNA synthesis. As we age or follow specific dietary restrictions, our bodies may require additional B12 supplementation. In this article, we will explore the 10 best B12 supplements available in 2025, helping you make an informed choice for your health needs.

SaleBestseller No. 1
Nature Made Vitamin B12 1000 mcg, Dietary Supplement for Energy Metabolism Support, 150 Softgels, 150 Day Supply
  • Energy metabolism support supplement: contains one 150 count bottle of Nature Made Vitamin B12 1000 mcg Softgels for a 150 day supply(1)
  • These Nature Made Vitamin B12 softgels help break down food into energy that your body can use all day long
  • B-12 vitamin helps support brain cell function and mood health (2)
  • Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
  • Adults take one B 12 vitamin softgel daily with water and a meal
SaleBestseller No. 2
Nature's Bounty Vitamin B12, Supports Energy Metabolism, Tablets, 1000mcg, 200 Ct
  • SUPPORTS CELLULAR ENERGY HEALTH (1): Nature’s Bounty B-12 vitamins aid in the conversion of food into cellular energy (1)
  • CARDIOVASCULAR SUPPORT (1): Vitamin B-12 is a commonly used vitamin taken to support the health of the cardiovascular and circulatory systems (1)
  • HELPS MAINTAIN HEALTHY NERVES (1): B-12 plays an important role in maintaining healthy nerve cells (1)
  • EASY TO SWALLOW COATED TABLETS: Nature’s Bounty B-12 tablets are coated, making them easier to swallow
  • FROM THE TRUSTED WELLNESS EXPERTS: Nature’s Bounty Vitamin B-12 tablets are a product of nearly 50 years of dedication to quality, consistency, and scientific research to make vitamins and nutritional supplements of unrivaled excellence
Bestseller No. 3
THORNE Vitamin B12 - as Methylcobalamin - Supports Heart & Nerve Health, Blood Cell Function, Healthy Sleep & Methylation* - Gluten, Dairy & Soy-Free - 60 Capsules
  • Methyl-B12: A form of vitamin B12 that is more readily used by the body*
  • Heart & Nerves: Supports heart health and nerve function*
  • Sleep: Helps maintain normal circadian rhythms to support restful sleep*
  • 3rd Party Contents Certified: This product has been third-party tested and certified to verify what's in the package matches what's on the label
  • Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners
SaleBestseller No. 4
Nature Made Vitamin B12 1000 mcg, Dietary Supplement For Energy Metabolism Support, 160 Time Release Tablets, 160 Day Supply
  • Energy metabolism support supplement: contains one 160 count bottle of Nature Made Vitamin B12 1000 mcg Time Release Tablets for a 160-day supply(1)
  • Nature Made B12 1000 mcg are dietary supplements that help break down food into energy that your body can use all day long
  • B-12 vitamin helps support brain cell function and mood health (2)
  • Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
  • Adults take one of these Nature Made B12 timed release tablets daily with water and a meal
Bestseller No. 5
Amazon Basics Vitamin B12 3000 mcg Gummies, Normal Energy Production and Metabolism, Immune System Support, Raspberry, 100 Count (2 per serving) (Previously Solimo)
  • Supports energy production by converting food to fuel and is essential for red blood cell formation. Promotes energy metabolism.*
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
  • Supports normal brain function and cognition. Supports healthy immune function*
  • Raspberry flavor with other natural flavors; Soft pectin-based vegan gummy
  • 100 gummies, a one-and-a half month supply (taken daily at listed serving size)
Bestseller No. 6
Pure Encapsulations B12 Folate - Energy Supplement to Support Nerves, Energy Metabolism & Cognitive Support* - with Vitamin B Folate as Metafolin - 60 Capsules
  • Premium Folate Supplement: Vitamin B12 and folate help convert carbohydrates into energy and break down proteins in the body; provides metabolism support*
  • Nervous System Support: Vitamin B12 (methylcobalamin) and folate (L-5-MTHF) support the nervous system, and function as hair, skin, and liver aids.*
  • Cognitive Support: Folate is essential for fetal neural development; B12 is an important nutrient for memory and cognitive support*
  • Supports Gut Health: Support G.I. tract thanks to the active form of the B12 vitamin, methylcobalamin; also a liver support supplement*
  • Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
SaleBestseller No. 7
Horbäach B12 Sublingual Methylcobalamin | 5000mcg | 120 Fast Dissolve Tablets | Vegetarian, Non-GMO and Gluten Free Supplement
  • SUBLINGUAL B-12: Enjoy the benefits of this Essential Vitamin in delicious Natural Berry Flavor!
  • POTENT FORMULA: Fast dissolve tablets feature 5,000 mcg of Vitamin B-12 as Methylcobalamin
  • EXPERTLY CRAFTED: Our vegetarian formula is backed by our commitment to purity and potency
  • HORBAACH MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
  • NATURALLY FREE OF: Gluten, Yeast, Milk, Lactose, Soy, Artificial Flavor, Preservatives, & Non-GMO
SaleBestseller No. 8
Nature's Bounty Vitamin B12, Supports Energy Metabolism and Nervous System Health, 500mcg, 100 Quick Dissolve Tablets
  • FOR ENERGY 100-count Vitamin B-12 500mcg Tablets; Nature’s Bounty Quick Dissolve B-12 vitamins play an important role in energy metabolism in the body(1); They help the body convert food into the fuel which is used to produce energy in the body(1)
  • FOR YOUR HEART Nature’s Bounty Vitamin B-12 is a commonly used vitamin taken to support the health of the cardiovascular and circulatory systems(1)
  • FOR YOUR NERVES Nature’s Bounty B-12 is an important vitamin for maintaining healthy nerve cells(1)
  • VEGETARIAN FORMULA Nature’s Bounty quick-dissolve Vitamin B-12 tablets are suitable for vegetarians; They are non-GMO gluten-free and sugar-free
  • FROM THE TRUSTED WELLNESS EXPERTS Nature’s Bounty Vitamin B-12 tablets are a product of 50 years of dedication to quality consistency and scientific research to make vitamins and nutritional supplements of unrivaled excellence
SaleBestseller No. 9
Garden of Life B12 - Vitamin Code Raw B-12 - 30 Capsules, 1,000mcg Whole Food B12 Methylcobalamin for Energy, Vegan Methylcobalamin B12 Vitamin plus Probiotics & Enzymes, Gluten Free Supplements
  • VITAMIN B-12: Essential to protect the body against anemia and support a healthy central nervous system, b 12 vitamin helps maintain healthy nerve cells and red blood cells and is also needed to make DNA, the genetic material in all cells
  • ANEMIA SUPPORT: This RAW, food created vitamin B12 provides metabolism support, mental & physical energy, central nervous system health, anemia support and digestive support
  • VEGETARIAN SUPPORT: Since B-12 is found predominantly in animal and dairy products, our vitamin b-12 tablet can help prevent deficiency-caused decreased energy, occasional constipation, anemia and fatigue
  • PROBIOTICS AND ENZYMES: Our plant based b-12 vitamin includes a RAW probiotic and enzyme blend for digestive support and vegetable blend for additional nutritional support
  • VEGAN VITAMIN B12: Our real food vegan b12 vitamin is RAW, Gluten Free, and Dairy Free with No Binders or Fillers
Bestseller No. 10
EZ Melts B12 Sublingual Vitamin 2,500 mcg, Methylcobalamin, Sugar-Free, 3-Month Supply
  • Bountiful Benefits in Every Bottle –– Help your body stay at its best with this B12 supplement. A B12 vegan vitamin supports healthy immune function and promotes mental clarity.* Aiding the body in breaking down food into energy, B vitamins are vital for overall well being*
  • Develop a Routine –– Tired of choking on chalky capsules? Don't stress over supplements with this EZ Melts B12 vitamin tablet that dissolves in your mouth. Nutrients will be readily available for absorption after ingestion to help support cellular health.* Get your dose of vitamin B-12 even on the go
  • Delicious Taste Without Compromise –– Sugary supplements seem counterintuitive. That's why our vegan B12 vitamin has zero sugar. The pleasant cherry flavor taste is created using plant-derived ingredients to make these vitamin B12 supplements easy on your tastebuds
  • No Corners Cut –– Stop settling for less. This supplement contains a bioactive form of B-12 vitamin vegan vitamin: methylcobalamin. To ensure effective nervous system support is delivered with every dose.* These tablets are also made with no artificial colors, flavors, or sweeteners
  • Manufactured in the USA –– These vegan vitamin B12 supplements are non-GMO with no pesky irritants like gluten or dairy. Every ingredient is globally sourced from US-based suppliers we are on a first-name basis with. So you can be confident in consistent quality

Why You Need Vitamin B12

Vitamin B12, also known as cobalamin, is primarily found in animal products, making it a concern for vegetarians and vegans. Deficiency can lead to fatigue, weakness, and neurological issues. Therefore, finding the right B12 supplement is essential for those who may not get enough from their diet.

Buying Guide for B12 Supplements

Before diving into our top picks, here are some factors to consider when choosing a B12 supplement:

1. **Form of B12**: B12 supplements come in various forms, including methylcobalamin, cyanocobalamin, and adenosylcobalamin. Methylcobalamin is often preferred for its bioavailability.

2. **Dosage**: Check the dosage per serving. The recommended daily allowance (RDA) for adults is 2.4 micrograms, but higher doses may be necessary for those with deficiencies.

3. **Delivery Method**: B12 supplements are available in tablets, capsules, sublingual forms, and injections. Choose one that fits your lifestyle.

4. **Additives**: Look for products free from artificial colors, flavors, and preservatives.

5. **Brand Reputation**: Opt for brands that are transparent about their sourcing and manufacturing processes.

Top 10 B12 Supplements

1. **Garden of Life Vitamin B12 Spray**

This organic B12 spray is a favorite among health enthusiasts. It contains methylcobalamin and is designed for quick absorption. The spray format makes it easy to use, and it’s free from artificial additives.

**Pros**: Organic, easy to use, quick absorption **Cons**: Some may find the taste unappealing

2. **Jarrow Formulas Methyl B12**

Jarrow Formulas offers a potent dose of methylcobalamin in a sublingual tablet. This form is known for its superior absorption and effectiveness. It’s also gluten-free and suitable for vegetarians.

**Pros**: High potency, sublingual delivery, vegetarian-friendly **Cons**: Tablets may be too large for some

3. **Nature Made Vitamin B12**

Nature Made is a well-known brand that provides a reliable B12 supplement in softgel form. Each softgel contains 1000 mcg of cyanocobalamin, making it an excellent choice for those looking for a straightforward option.

**Pros**: Easy to swallow, affordable, widely available **Cons**: Cyanocobalamin may not be as effective as methylcobalamin

4. **Solgar Methylcobalamin B12**

Solgar’s methylcobalamin B12 is a high-quality option that comes in a cherry-flavored sublingual tablet. It’s non-GMO and free from gluten, dairy, and soy, making it suitable for various dietary needs.

**Pros**: Great taste, high-quality ingredients, non-GMO **Cons**: Higher price point

5. **MaryRuth Organics B12 Gummies**

For those who prefer a tasty treat, MaryRuth Organics offers B12 gummies that are vegan and free from common allergens. Each gummy contains 500 mcg of methylcobalamin, making it a fun way to boost your B12 intake.

**Pros**: Delicious flavor, vegan-friendly, easy to take **Cons**: Lower dosage per serving

6. **Kirkland Signature Vitamin B12**

Kirkland Signature provides a budget-friendly option with its B12 tablets. Each tablet contains 1000 mcg of cyanocobalamin, making it a solid choice for those looking for an economical supplement.

**Pros**: Cost-effective, high dosage, easy to find **Cons**: Cyanocobalamin may not be as effective for everyone

7. **Life Extension Methylcobalamin B12**

Life Extension offers a high-potency methylcobalamin B12 supplement in a lozenge form. This product is designed for optimal absorption and is free from common allergens.

**Pros**: High potency, excellent absorption, allergen-free **Cons**: May be pricier than other options

8. **Nutricost Vitamin B12**

Nutricost provides a straightforward B12 supplement in capsule form. Each capsule contains 5000 mcg of cyanocobalamin, making it suitable for those with significant deficiencies.

**Pros**: High dosage, affordable, easy to take **Cons**: Cyanocobalamin may not be the best choice for everyone

9. **Thorne Research Methylcobalamin**

Thorne Research is known for its high-quality supplements, and their methylcobalamin B12 is no exception. This product is free from gluten, dairy, and soy, making it suitable for various dietary restrictions.

**Pros**: High-quality ingredients, allergen-free, effective **Cons**: Higher price point

10. **B12 Energy Boost by Pure Encapsulations**

This unique formula combines B12 with other energy-boosting nutrients. It’s designed for those looking to enhance their energy levels while supporting overall health.

**Pros**: Comprehensive formula, high-quality ingredients, effective **Cons**: More expensive than standard B12 supplements

Conclusion

Choosing the right B12 supplement can significantly impact your health, especially if you are at risk of deficiency. Whether you prefer gummies, sublingual tablets, or softgels, there’s a B12 supplement on this list that will meet your needs. Always consult with a healthcare professional before starting any new supplement regimen to ensure it aligns with your health goals. With the right B12 supplement, you can support your energy levels, nerve function, and overall well-being.

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